Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 1.574


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMARCA1chrX_-_128485062-0.674.7e-03Click!
SMARCA5chr4_+_1446540050.621.0e-02Click!
SMARCC2chr12_-_548695680.621.1e-02Click!
NCOR1chr17_-_160595140.282.9e-01Click!
NCOR2chr12_-_1236179620.126.7e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_26665213 4.115 EVI2B
ecotropic viral integration site 2B
chr19_-_44518516 3.078 NM_004877
 GMFG
glia maturation factor, gamma
chr2_+_143603439 3.069 ARHGAP15
Rho GTPase activating protein 15
chrX_+_78087484 3.011 NM_014499
NM_198333
 P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr2_+_143603368 3.006 NM_018460
 ARHGAP15
Rho GTPase activating protein 15
chr1_-_149004916 2.961 NM_004079
 CTSS
cathepsin S
chr19_-_44518465 2.850 GMFG
glia maturation factor, gamma
chr12_-_15005761 2.805 NM_001175
 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_196874839 2.574 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_32512298 2.480 NM_001042771
 LCK
lymphocyte-specific protein tyrosine kinase
chr14_-_106184988 2.369 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_73826244 2.357 NM_000265
 NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr5_-_149772469 2.339 NM_001025159
NM_004355
NM_001025158
 CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr5_-_94442941 2.280 MCTP1
multiple C2 domains, transmembrane 1
chr15_+_86983038 2.245 NM_002201
 ISG20
interferon stimulated exonuclease gene 20kDa
chr20_+_44180296 2.239 NM_001250
NM_152854
 CD40

CD40 molecule, TNF receptor superfamily member 5

chr17_-_26665144 2.214 EVI2B
ecotropic viral integration site 2B
chr14_+_75058518 2.149 NM_006399
 BATF
basic leucine zipper transcription factor, ATF-like
chr1_-_149004879 2.101 CTSS
cathepsin S
chr5_-_138753443 2.097 NM_016459
 MZB1
marginal zone B and B1 cell-specific protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
4.59 2.31e-05 GO:0034340 response to type I interferon
4.42 1.09e-04 GO:0060337 type I interferon-mediated signaling pathway
4.42 1.09e-04 GO:0071357 cellular response to type I interferon
2.65 1.08e-03 GO:0019221 cytokine-mediated signaling pathway
2.57 4.93e-03 GO:0046649 lymphocyte activation
2.39 1.05e-02 GO:0071345 cellular response to cytokine stimulus
2.34 8.41e-03 GO:0045321 leukocyte activation
2.23 3.61e-04 GO:0045087 innate immune response
2.05 4.99e-02 GO:0034097 response to cytokine stimulus
2.04 1.51e-07 GO:0006955 immune response
1.78 1.86e-07 GO:0002376 immune system process
1.63 4.86e-02 GO:0006952 defense response

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.45 1.31e-02 GO:0005654 nucleoplasm
1.39 8.00e-03 GO:0031981 nuclear lumen
1.35 9.38e-03 GO:0044428 nuclear part
1.20 3.59e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.34 2.63e-02 GO:0003677 DNA binding
1.31 4.12e-03 GO:0003676 nucleic acid binding
1.14 1.81e-02 GO:0005515 protein binding